Add the chicken breasts to your crockpot and season with garlic powder, onion powder, Kinder’s Buttery Garlic & Herb seasoning, and ranch seasoning.
Add the block of cream cheese and pour the entire jar of Frank’s RedHot Buffalo Wings Sauce over everything.
Cover and cook on HIGH for 3 hours, or until the chicken is fully cooked and tender.
Shred the chicken directly in the crockpot and mix it into the buffalo cream cheese sauce.
Add the cooked macaroni pasta, mozzarella cheese, cheddar cheese, and a splash of heavy cream.
Mix everything together until the cheese is melted and the buffalo chicken mac and cheese is creamy and well combined.
Serve hot and enjoy.